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Salmonella is an important cause of foodborne disease in humans throughout the world and is a significant cause of morbidity, mortality, and economic loss [1-6].
Human salmonellosis is the second ranking foodborne disease in most European countries, only exceeded by campylobacteriosis.
This approach requires a collection of temporally and spatially related isolates from vari- ous sources and humans, and is consequently facilitated by an integrated foodborne disease surveillance program focused on the collection of isolates from the major food-animal reservoirs of foodborne pathogens and from humans [60].
The fraction of the burden of foodborne disease that is associated with outbreaks varies between pathogens but is typically smaller than the correspondent to sporadic disease.
Case-control studies of sporadic infections are the most commonly applied approach for identifying possible exposures for sporadic foodborne disease includ- ing salmonellosis.
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